SnapGene Version 4.3.5

SnapGene 4.3.5 was released on March 20, 2019.

New Functionality

• Added Ozyme DNA ladders.(Requested by Laetitia Attaiech)
• Added support for the /submitter_seqid qualifier for "source" features.(Requested by Novozymes)
• Added the capability to open and convert Vector NTI® AlignX files (.apr and aprx extensions).

Enhancements

• Made extensive optimizations that speed responsiveness for certain configurations.
  (Requested by Paula Patterson and others)
• Sped up the dragging of trimmed ends of aligned sequences when the aligned sequences are viewed as double-stranded DNA.
• Improved accuracy when computing protein MW values.(Requested by Eric Fang)
• Made various color and textual enhancements.
• Added a setting under Preferences → File to enable preservation and transfer of "source" features when simulating various types of DNA manipulations.(Requested by Novozymes)
• Enabled import of a listed file by double-clicking when importing online sequences from SnapGene or Addgene.

Fixes

• Enabled contig assembly with only two sequences.
  (Reported by Rony Orobio)
• Fixed an issue with loading alignments that wrap around the numerical origin.
  (Reported by Sofie Aesaert)
• Ensured proper computation of the number of DNA molecules when using a comma instead of a decimal in the weight value.
  (Reported by Tuisku Suoranta)
• Enabled the use of various non-native file formats when computing multiple sequence alignments.
  (Reported by Neal Waxman)
• Fixed an issue with copying information from Microsoft Office and pasting it into feature qualifier fields and other fields.
  (Reported by Mick Chandler)
• Improved import of files into the Assemble Contigs dialog.
  (Reported by Min-Hyeok Cha)
• Prevented automatic choice of a nonstandard genetic code when inserting codons into an empty synthetic construct.
• Ensured correct display of small segments of full-length features in circular maps.
• Improved the import of reverse directional translated BED and Genome Compiler features.
• Removed the "Prioritize this feature..." checkbox for protein site and bond features because it had no effect.
• Improved stability when canceling during import of a Vector NTI database.
• Enabled BLAST searches when individual sequences are selected in a multiple sequence alignment.
• Omitted actions that did not apply when viewing various files types in collections.
• Ensured that the collection folder icon is always correctly set.
• Improved the "Edit Features" behavior when the DNA feature type is changed, with respect to marking features as translated and ensuring that they have appropriate directionality.
• Improved focus and selection color when moving sequences aligned to a reference DNA sequence up or down in the list box.
• Ensured that changes in methylation in an open document propagate to cloning dialogs in which that same document is displayed.
• Improved the display of restriction fragments in a cloning dialog if an enzyme that is always blocked by methylation is chosen.
• Improved auto-completion of enzyme names.
• Fixed an issue with properly identifying the amount of available memory, especially on systems with over 4 Gb of memory.
• Prevented a rare issue of missed matches that wrap around the numerical origin in extremely small sequences.
• Improved the behavior of PCR products in the Mutagenesis dialog.
• Corrected an empty warning message in the Mutagenesis dialog.