Changes in version 6.1 (Jul 5, 2022)

New Functionality:

• New Golden Gate Assembly simulation tool, either using existing Type IIS enzymes or through automated primer and overhang design
• New Secondary Structure view tab for single stranded RNA sequences. Structures calculated using the ViennaRNA package
• Added support for Dark mode, automatically using the OS settings for macOS and Windows
• Native support for Apple Silicon machines
• Enabled customization of content exported to GenBank including LOCUS field identifier and feature export options

Enhancements:

• Added "Synthetic Protein" and "Unknown" options for the Source attribute in the description panel
• Added DNA ladders from OriGene
• Ladder fragment lengths are now displayed in the fragment list in agarose gels
• Added LOBSTR to the list of E. coli strains
• Improved the detection and simplified the display of primer hybridizations with 3' overhangs
• Provide a cancel option when a message is shown indicating an unknown or not installed custom feature type must be addressed before proceeding with editing or duplicating one or more features
• Added links to SnapGene Academy
• Extensive optimizations
• Various textual and layout enhancements

Fixes:

• Improved stability
• Fixed various memory leaks
• Fixed issues with opening some GenBank files
• Ensured the fragment list in cloning dialogs continue to refresh when either enzyme is manually cleared
• Improved text spacing after punctuation characters on macOS
• Fixed an issue that prevented the Enzymes view "Select Range" context menu command from working
• Improved mouse pointer shape when over links in Collection windows
• Fixed or improved various links to SnapGene.com pages
• Fixed an issue where cloning dialogs could get stuck generating the product
• Fixed an issue where some windows omitted the title bar on Windows
• Fixed an issue where selected codons were not always shown using a white foreground in Sequence view
• Fixed an issue where Ready to Clone was still shown after adding or removing a fragment, even if cloning was no longer possible
• Use the default file format specified in Preferences when exporting alignments
• Fixed an issue with Geneious file import where features in protein sequences could erronously be translated
• Fixed an issue with Geneious file import where introns in nucleotide sequences imported were translated
• Fixed an issue where the Enter key in the numpad was not responsive when a combo box or line edit had focus on macOS
• Improved image quality when exporting to EMF format
• Improved display of checkboxes on Windows
• Fixed dropdown menus in Windows which sometimes had clipped text
• Fixed issues with the display and behaviour of default buttons in dialogs
• Fixed an issue with files appearing disabled in the macOS file explorer when they were able to be chosen
• Fixed an issue that prevented pasting into the Find control in the Open and Save As dialogs on macOS
• Fixed an issue that prevented importing AddGene sequences that contain reserved characters in the file name into a Collection on Windows
• Corrected an issue that resulted in an incredibly wide window when importing a database from CSV format that lacks headers into a Collection
• Fixed an issue where ancestral sequences that cannot be resurrected were shown as blue links in the text format of History view
• Fixed an issue where the Add Primer command could add a primer to an open DNA window even if a Collection window was active when the command was triggered
• Fixed an issue with the display of an amino acid selection highlighting within a translation
• Fixed an issue on Ubuntu whereby AB1 files in a Collection opened in SnapGene Viewer if installed
• Fixed some issues with dialogs opening in strange positions, such as on a different monitor
• Addressed a stability issue when editing a collection description.
• Fixed an issue with importing mixed content types from NCBI
• Fixed various issues with the sequence name when importing from NCBI, especially when using the COMPLEMENT operator.
• Fixed a number of printing issues on Windows when the operating system is set to scale all content to 100% or 150%.
• Fixed the appreance of the transformation strand menu in the Change Methylation dialog on Windows.
• Fixed printing the header for multiple sequence alignments on Windows using 100-200% scaling.
• Improved printing margins on Windows.
• Improved print quality of mutiple sequence alignments on Windows.
• Imporved the default height of the Insert Codons dialog.
• Improved the horizontal alignment of text in the fragmnets list shown in Agarose Gel documents.
• Improved the display of site feature labels in multiple sequence alignemnts.
• Fixed an issue where browsed or edited common features are not realible shown with all relevant qualifiers in the Browse Common Features dialog.
• Repliably respect the "Detect either an exact protein match or approximate DNA match" setting when detecting common features.
• Improved margins when printing on Windows
• Fixed horizontal alignment of enzyme names when printing on Windows.
• Addressed various issues when printing on Windows with the display scaling set to 200% or higher.
• Improved the width of spinboxes on Windows.
• Avoid elliding menu commands on Windows
• Fixed various issues that made it difficult to install software updates on Windows.
• Improved behavior of progress bar when when installing software updates on macOS.